Benzaldehyde, 4-bromo-2-(trifluoromethoxy)-

Benzaldehyde, 4-bromo-2-(trifluoromethoxy)- - Names and Identifiers

Name	4-Bromo-2-(trifluoromethoxy)benzaldehyde
Synonyms	4-Bromo-2-(trifluoromethoxy)benzaldehyde benzaldehyde, 4-bromo-2-(trifluoromethoxy)- Benzaldehyde, 4-bromo-2-(trifluoromethoxy)- 2-trifluoromethyl-methoxy-4-bromobenzaldehyde
CAS	220996-80-5
InChI	InChI=1/C8H4BrF3O2/c9-6-2-1-5(4-13)7(3-6)14-8(10,11)12/h1-4H

Benzaldehyde, 4-bromo-2-(trifluoromethoxy)- - Physico-chemical Properties

Molecular Formula	C8H4BrF3O2
Molar Mass	269.02
Density	1.706
Boling Point	244 ºC
Flash Point	101 ºC
Vapor Presure	0.0307mmHg at 25°C
Storage Condition	under inert gas (nitrogen or Argon) at 2-8°C
Refractive Index	1.518

Benzaldehyde, 4-bromo-2-(trifluoromethoxy)- - Introduction

4-Bromo-2-(trifluoromethoxy)benzaldehyde is an organic compound with the chemical formula C8H5BrF3O2.

Nature:
-Appearance: colorless or yellowish Crystal
-Melting point: 44-48 ° C
-Boiling Point: 244-245 ° C
-Density: 1.834g/cm3
-Solubility: Soluble in organic solvents such as ethanol, dimethylformamide, etc., insoluble in water

Use:
- 4-Bromo-2-(trifluoromethoxy)benzaldehyde can be used as an intermediate in organic synthesis and is widely used in the synthesis of drugs and pesticides and other compounds.

Method:
The preparation of 4-Bromo-2-(trifluoromethoxy)benzaldehyde can be carried out by the following steps:
1. First, an O-Bromo group-containing phenol is reacted with trifluoromethyl alcohol in the presence of hydrofluoric acid to produce a trifluoromethoxy compound.
2. Next, under alkaline conditions in the presence of a trifluoromethoxy compound, cuprous bromide is added to carry out bromination reaction to produce the target product.

Safety Information:
- 4-Bromo-2-(trifluoromethoxy)benzaldehyde should be used with caution and attention should be paid to protective measures.
-It may be irritating to the eyes, skin and respiratory tract, and personal protective equipment such as protective gloves and goggles should be worn when in contact.
-During use and storage, keep away from heat and fire sources, and avoid contact with oxidants and combustibles.
-If swallowed or inhaled, seek medical attention immediately.

Last Update：2024-04-09 21:01:54